Study • Wisdom

How It Works

Check out this short, animated film to learn how you can participate in the Wisdom Study.

If you would like a readable summary of this video, click here.

Study Details

Read on to learn more about who can join and how the participation process.

  • QuestionMark
  • It's Simple

    It's so easy! All of the steps can be completed at home at your own convenience. Just click here to get started, and you will be directed to a page in which you can tell us more about yourself.

    Once your eligibility is confirmed, you will be asked to sign a consent form and fill our additional surveys online. We are currently able to enroll women* who:

    • Are 40-74 years old
    • Have no personal history of breast cancer or ductal carcinoma in situ (DCIS)
    • Have no history of mastectomy in both breasts
    • Receive care at participating center
    • Are covered by a participating insurer

    Please know that our enrollment criteria will be expanding as the study progresses, so if you don't qualify at this time, please check back later to see if you may qualify!

    * Due to the specific measures of this particular study, we are unable to enroll transgender women in this study.
  • Medical Tablet
  • It's Safe

    After filling out the questionnaires, you will be randomly assigned into one of two screening groups: Routine Annual Screening or Personalized Screening. In the event you have a strong preference to participate in the Routine Annual or the Personalized Screening Group, you will have the option to choose your study arm.

    No one will be getting any less screening than current guidelines suggest. You will have the peace of mind knowing that your own personal health history is being considered whatever your recommendation.

    All Wisdom Study participants will have a personal evaluation to determine your screening recommendation based on your answers to the health history questionnaire (and your mammogram report if you have had one). You will also receive information about how to prevent breast cancer and help keep yourself healthy.
  • Group Assignment
  • Personalized vs Routine Annual Screening

    • Personalized Screening Group: You will get a genetic test kit sent to your home, which is a saliva sample to help determine your risk of breast cancer and breast screening recommendations. Higher risk women will screen every 6 months, average risk women every year, and lower risk women will be advised to screen every other year.

    • Routine Annual Screening Group: You will be considered at average risk and you will be advised to start screening at age 40 and repeat mammograms once a year. In the event you are determined to be at higher risk for breast cancer, you will be advised to screen every 6 months.
  • Having Wisdom
  • It's Scientific

    Your participation in this study will help us end the confusion of when to start and how often women should be screened for breast cancer, which should increase the benefits of screening—catching life threatening cancer that would have been missed without screening-- while decreasing the harms of screening, such as false alarms and unneeded biopsies that cause a lot of worry and stress.

    You will have access to the latest and most up to date research on breast cancer screening, and you can contact the study team anytime to get your own breast health questions answered during the duration of the study.

    We believe this study has the potential to transform breast cancer screening, and we hope you will be part of it! Together, we can find a better way forward for ourselves, our friends, sisters, and daughters, and future generations of women.

  • Randomly Assigned

    The majority of women in the study choose this option. Because randomization increases the study's scientific validity, this option helps Wisdom the most.

  • Self-selected

    The minority of women in the study choose this option. You choose which screening group you are assigned to.

  • Personalized

    Your personal breast cancer risk will determine your recommended screening schedule.

  • Routine Annual schedule

    You will receive a routine annual mammogram with the same quality care we are known for.


With your help, we can find answers. Share your Wisdom.